Work

Sickle Cell Disease - Risk Factors, Symptoms, Diagnosis, Treatment, and Prevention

Year: 2025

Type: article

Abstract: Sickle cell disease (SCD) is a genetic blood disorder where red blood cells become rigid and sticky, forming crescent or sickle shapes, causing blockages, pain, and organ damage. SCD is identified through newborn screening or genetic testing, detecting abnormal hemoglobin. Symptoms like anemia, pain crises, and organ damage aid diagnosis. Treatment aims to relieve symptoms and prevent complications. It includes pain management, hydration, blood transfusions, and medications to reduce complications like infections and stroke. Vaccinations, especially against pneumonia and influenza, are crucial for preventing complications. Regular check-ups and early intervention are vital, along with maintaining a healthy lifestyle. Genetic Counseling helps individuals understand SCD inheritance and make informed family planning decisions. Prenatal testing detects SCD early, enabling choices about pregnancy and treatments.

Source: The American journal of patient health info.

DOI: 10.69512/ajphi.v2i1.46

Authors: Prabha Bhandari, Gauri Adhikari, Pradeep Khatiwada

Institutions: Kathmandu University, Nepalese Army Institute of Health Services, B.P. Koirala Institute of Health Sciences

Language: English

Topic: Hemoglobinopathies and Related Disorders

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4407277936

FWCI: 0.541

Cites:

Cited by: 1

Related to: 10