Work

Mechanical characterization of the human femoral vein wall and its valves

Year: 2025

Type: article

Abstract: = 2.3 ± 1.0 N/mm). A distinct anisotropy of the mechanical properties could only be detected for PFA fixed material when comparing longitudinal and circumferential tensile direction. Resultant mean compliance values over all segments and measuring positions of the vein segments for the analyzed pressure stages were in the range from 18.16 to 3.78 %/100 mmHg and showed a distinct decrease with increasing pressure. Fixation (FA, PFA) alters the elastomechanical behavior, but the parameters were still in a similar order of magnitude considering the naturally occurring variability. Thus, testing of fixed tissue appears to be as appropriate as the use of this material for ex vivo testing. The provided material data of femoral veins (longitudinal and circumferential) as well as venous valve leaflets may serve as basis for numerical models, e.g. for the development of artificial venous valves.

Source: Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials

DOI: 10.1016/j.jmbbm.2025.106938