A new C-peptide minimal model to assess β-cell responsiveness to glucagon in individuals with and without type 2 diabetes
Year: 2025
Type: article
Abstract: In this study, we propose a new mathematical model able to quantify C-peptide secretion and β-cell responsivity in response to a glucagon bolus in individuals without and with type 2 diabetes. We show that individuals with type 2 diabetes exhibit reduced β-cell responsivity to glucagon.
Institutions: University of Padua, Mayo Clinic
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4407342433