Preferences for treatment outcomes in rectal cancer: A discrete choice experiment among patients and healthy volunteers
Year: 2025
Type: article
Study design: Observational Study
Abstract: AIM: Treatment for rectal cancer can leave patients with a permanent stoma or bowel dysfunction. In this work we aimed to examine preferences for treatment outcomes among people with and without rectal cancer. METHOD: Our discrete choice experiment examined the effect of risk of cancer recurrence, presence of a stoma and bowel dysfunction on treatment preferences in 372 rectal cancer patients without a stoma, 269 with a stoma and 204 people without cancer. RESULTS: Predictors of treatment preferences differed significantly between all groups (p < 0.0001). Avoiding a stoma was more important to stoma-naïve groups, while avoiding bowel dysfunction was more important to those with superior function. Reducing the risk of recurrence was valued highly, and equally, across the groups. CONCLUSION: Experience of a stoma or bowel dysfunction resulted in higher tolerance of those treatment outcomes. Hearing from patients living with different treatment outcomes could help prepare newly diagnosed patients, and facilitate informed decision-making where patients have a choice.
Source: Colorectal Disease
DOI: 10.1111/codi.70021
Authors: Anne Miles, Robert James Campbell Steele, Gemma Hutton, Stephen Morris
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,480
Funders: Bowel Cancer UK, Bowel Research UK
OpenAlex ID: W4407349191
