Work

Preoperative Chest CT Myosteatosis Indicates Worse Postoperative Survival in Stage 0–IIB Non–Small Cell Lung Cancer

Year: 2025

Type: article

Abstract: < .001, respectively). There was no evidence of an association between OS and skeletal muscle index, SAT index, and SAT density. The predictive performance (concordance) increased from 0.723 (95% CI: 0.686, 0.753) to 0.731 (95% CI: 0.692, 0.762) after including myosteatosis markers. Conclusion Increased thoracic myosteatosis markers were associated with worse OS after lobectomy or bilobectomy of stage 0-IIB NSCLC, independent of skeletal muscle index, SAT index, and SAT density, and improved OS prediction. © RSNA, 2025

Source: Radiology

DOI: 10.1148/radiol.240282

Authors: Lea Mantz, Nathaniel D. Mercaldo, Judit Simon, Philipp Kaess, Kai Yang, Anna-Sophia W. Dietrich, P. Erik Tonnesen, Amelie S. Troschel, J. Peter Marquardt, Daniel A. Sehi, Cylen Javidan, Jonathan H. Chung, Henning A. Gaissert, Mark K. Ferguson, Florian J. Fintelmann

Institutions: Semmelweis University, Johannes Gutenberg University Mainz, Washington University in St. Louis, Massachusetts General Hospital, University Medical Center of the Johannes Gutenberg University Mainz, University Medical Center Hamburg-Eppendorf

Language: English

Topic: Lung Cancer Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4407368931

FWCI: 15.19

Cites: 33

Cited by: 25

Related to: 10