Research Progress on the Mechanism of Action of Traditional Chinese Medicine Extracts in the Prevention and Treatment of Periodontitis
Year: 2025
Type: article
Abstract: Periodontitis is an inflammatory infectious disease affecting the periodontal supporting tissues and is the primary cause of tooth loosening and tooth loss in adults. Clinically, supragingival scaling, subgingival scaling, root planing, and other basic periodontal treatments, often combined with antibiotic therapy, are commonly employed with moderate efficacy. However, the increasing prevalence of antibiotic resistance and associated adverse reactions has become a growing concern. Recent studies have demonstrated the significant impact of traditional Chinese medicine (TCM) extracts in both the prevention and treatment of periodontitis, exhibiting remarkable effectiveness. This review explores the role and mechanisms of TCM extracts in the prevention and treatment of periodontitis, providing a reference for further elucidation of their mechanisms and a theoretical basis for the development of Chinese herbal medicine-based care products.牙周炎是一种发生于牙周支持组织的炎症性感染性疾病，是成年人牙齿松动和脱落的主要原因。在临床上，龈上洁治、龈下洁治、根面平整等牙周基础治疗，结合抗生素治疗，通常都有较好的疗效。然而，抗生素耐药性和不良反应越来越普遍。近年来，大量的研究表明，中药提取物在预防和治疗牙周炎方面具有显著的影响，具有特殊的效果。因此，本文就中药提取物在牙周炎防治中的作用及机制进行综述，为深入阐明中药提取物防治牙周炎的作用机制提供参考，并为中草药护理产品的开发提供理论依据。
Authors: Ke Tian, Rao Lu, Tang Jing
Institution: Zunyi Medical University
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: bronze
Awards: G1438623677, G4444903408
OpenAlex ID: W4407398244