High-energy-density acoustofluidic device using a double-parabolic ultrasonic transducer
Year: 2025
Type: article
Abstract: High-acoustic-energy-density acoustofluidic devices are necessary to make this technology a viable option for clinical applications in the biomedical field. We present a mechanical interface that enables delivery of a high-amplitude acoustic field inside a fluid cavity by translating the vibrations from two large piezoelectric elements into a microfluidic chip. The study comprises both experimental characterization of a double-parabolic metallic acoustic waveguide and simulations of its working mechanism in two dimensions. We could focus 4.9-µm polystyrene particles at a flowrate of 5 ml/min, corresponding to an average retention time of 13.5 ms for particles in the actuated area. Moreover, we measured the acoustic energy density in the channel at stopped-flow condition, obtaining an average value of 1207 J / m 3 and a maximum value of 2977 J / m 3 with an input electrical power of 1.5 W. By comparing the simulation results with laser-Doppler vibrometer measurements, we confirmed that transverse sound waves play a significant role in the working mechanism of the double-parabolic structure, thus paving the way for further future optimization of the waveguide design.
Source: Physical Review Applied
Authors: Enrico Corato, Ola Jakobsson, Wei Qiu, Takeshi Morita, Per Augustsson
Institutions: Lund University, The University of Tokyo
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
Awards: G2893429763, G434337789, Microscale acoustofluidics-enabled single cell mechanotyping and nanoparticle separation, High-power ultrasonic SAW/Lamb wave excitation using longitudinal / transverse wave mode conversion and their applications, Akustisk gradientfokusering för separation av biopartiklar
OpenAlex ID: W4407407193