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A bacterial antiviral system detects and directly fights against infection

Year: 2025
Type: article
Abstract: Bacteria have developed many strategies to defend themselves from phages — the viruses that infect them. The Zorya defence system uses a previously undescribed antiviral strategy. An inner-membrane-anchored complex detects phage infection, resulting in recruitment of enzymes inside the cell that digest incoming phage DNA, thereby rapidly preventing infection. Protein complex in bacterial cell membrane acts like a rotary motor to recruit DNA-degrading enzymes to defend against phage infection.
Source: Nature
Language: English
Subfield: Ecology
Open Access status: hybrid
Estimated APC paid: $12,690
OpenAlex ID: W4407407367
FWCI: 1.065
Cites: 4
Cited by: 2
Related to: 10