Work

Massively parallel in vivo Perturb-seq screening

Year: 2025

Type: review

Source: Nature Protocols

DOI: 10.1038/s41596-024-01119-3

Authors: Xinhe Zheng, Patrick C. Thompson, Cassandra M. White, Xin Jin

Institution: Scripps Research Institute

Language: English

Topic: Single-cell and spatial transcriptomics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, McKnight Endowment Fund for Neuroscience, Pew Charitable Trusts, Simons Foundation, Larry L. Hillblom Foundation, Esther A. and Joseph Klingenstein Fund, G. Harold and Leila Y. Mathers Foundation, Simons Foundation Autism Research Initiative, National Institute of Mental Health, National Human Genome Research Institute

Awards: G3030292564, G342162296, G6583531119, In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissues, Scalable functional analysis of neuropsychiatric risk genes with spatially integrated in vivo Perturb-seq

OpenAlex ID: W4407410223

FWCI: 1.317

Cites: 92

Cited by: 15

Related to: 10