Year: 2025
Type: article
Abstract: Over the past few decades, our understanding of substance use disorders (SUD) has been reshaped by evidence from neuroscience, which suggests that SUD are characterized by specific neuromarkers that transcend traditional diagnostic boundaries and act as pre-diagnostic markers that could be targeted through preventive attempts. Connectivity-based neuromarkers or brain networks have emerged as a promising framework, providing new insights into the neurocognitive mechanisms of SUD. Utilizing this data-driven framework assists prevention and intervention developers in offering a non-judgmental insight for adolescents regarding the potential vulnerability of neurocognitive systems to continued substance use. Given the importance of such awareness, this paper proposes a neural network-informed approach based on research domain criteria (RDoC) to characterize the content of neuroscience-informed psychoeducation designed for SUD. Furthermore, we argue that various features related to content and structure need to be considered when developing such interventions delivered through digital platforms (e.g., apps and websites). Finally, we introduce a theory-driven app called "NIPA", developed with the aim of increasing adolescents' awareness and resilience to the effects of drugs and other emotional triggers on brain and cognitive functions.
Source: Frontiers in Psychiatry
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
Funders: Virginia Commonwealth University, Georgia Clinical and Translational Science Alliance, National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, Fogarty International Center, National Center for Research Resources, National Center for Advancing Translational Sciences
Awards: G1358720175, G2481876672, G289535915, G3639572947, G3893063192, A Longitudinal Study of Genes, Environment and Alcohol Misuse In College Students, Cross Species Characterization of Gene Networks in Acute Responses to Ethanol, G6810423065, Genetics, Romantic Relationships, and Alcohol Misuse in Emerging Adulthood, Cross-species investigation of gene networks for ethanol-related behaviors
OpenAlex ID: W4407416462
