Work

In vivo efficacy of a refillable intrawound drug delivery device in a sheep model of biofilm-compromised open fracture-related infection

Year: 2025

Type: article

Abstract: CFU. The hypothesis was supported. The Pouch received Breakthrough Device Designation by the FDA, is being transitioned toward clinical trials, and is a potential solution to the long-standing problem of open fracture-related infection.

Source: Biofilm

DOI: 10.1016/j.bioflm.2025.100262

Authors: Dustin Williams, David Rothberg, Walker Kay, Lisa Nehring, Robert Falconer, Richard Tyler Epperson, Brooke Kawaguchi, Carolyn Ardizzone, Brian Barnum, Nicholas Ashton

Institutions: Uniformed Services University of the Health Sciences, University of Utah, Noorda College of Osteopathic Medicine, Rocky Vista University, University of New Mexico

Language: English

Topic: Orthopedic Infections and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,140

Funders: Office of Research, Utah State University, U.S. Department of Defense, Uniformed Services University of the Health Sciences, Defense Health Agency

OpenAlex ID: W4407461931

FWCI: 5.182

Cites: 71

Cited by: 6

Related to: 10