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Symptomatic Relief of Skin Toxicities Induced by EGFR TKI Therapy: Use of Bicarbonate Ion Bath Salts

Year: 2025

Type: article

Abstract: Introduction: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapy for non–small cell lung cancer with EGFR gene mutation is associated with a high occurrence of skin disorders, such as dermatitis, dry skin, and paronychia. Moisturizers, steroids, and oral minocycline are used to treat these adverse effects, with limited efficacy. We conducted a pilot study to investigate the usefulness of bicarbonate ion bath salts, which are known to have excellent moisturizing properties, for treating skin disorders caused by EGFR TKI therapy.

Source: Annals of Cancer Research and Therapy

DOI: 10.4993/acrt.33.5

Authors: Mitsuhiro Kamimura, Tatsuya Ibe, Atsuto Mouri

Institutions: National Hospital Organization, National Disaster Medical Center

Language: English

Topic: Chemotherapy-related skin toxicity

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4407479389

FWCI:

Cites: 19

Cited by:

Related to: 10