Work

Cocoa modulates cardiovascular remodeling and metabolism of female and male Wistar rats subjected to early weaning

Year: 2024

Type: article

Abstract: Breastfeeding is crucial for infants, and early weaning (EW) increases the risk of cardiovascular (CV) and metabolic diseases later in life. Thus, we investigated the impact of cocoa supplementation on these parameters in rats subjected to EW. Female and male Wistar rats weaned on postnatal day 21 (PND21, C) or PND18 (EW) received a standard chow diet (SC) or SC supplemented with 10% cocoa powder (Co) from PND0 to PND90. EW affected food intake, body mass, body composition, blood glucose, blood lipids, and heart’s left ventricle dimensions, and cocoa consumption improved most of these parameters with sexual dimorphism. The study highlights cocoa's potential as a non-pharmacological strategy to mitigate cardiovascular risks associated with EW.

Source: Caderno Pedagógico

DOI: 10.54033/cadpedv21n13-375

Authors: Letícia Monteiro da Fonseca Cardoso, Juliana Arruda de Souza Monnerat, Vanessa Morales Torres, Vitor Lima Simões, Sergio Girão Barroso, Bianca Martins Gregorio, Anissa Daliry, Caroline Fernandes-Santos, Gabrielle de Souza Rocha

Institutions: Universidade Federal Fluminense, Fundação Oswaldo Cruz

Language: English

Topic: Food Chemistry and Fat Analysis

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: diamond

OpenAlex ID: W4407488116

FWCI:

Cites: 30

Cited by:

Related to: 10