Work

Lumbosacral plexopathy following alcohol-induced rhabdomyolysis: a case report

Year: 2025

Type: article

Abstract: Objective We present a rare case of lumbosacral plexopathy secondary to alcohol-induced rhabdomyolysis. Case description A 58-year-old male patient was admitted to the intensive care unit (ICU). He reported a sensation of weakness in both legs and a tingling sensation in his feet upon awakening post binge drinking. Magnetic resonance imaging (MRI) of the thoracic and lumbar spine did not reveal any intraspinal abnormalities. However, an MRI showed lesions with abnormal intensities in both paraspinal muscles. Serum creatine phosphokinase level was markedly elevated. A diagnosis of lumbosacral plexopathy following alcohol-induced rhabdomyolysis was determined by clinical findings, MRI data and an electrophysiological evaluation. Upon discharge, lower limb strength was significantly improved. Discussion In severe rhabdomyolysis, the resulting kidney injury and electrolyte imbalances can lead to systemic complications, including peripheral neuropathy or plexopathy. The exact mechanisms by which this occurs are not fully understood, however it is believed that the accumulation of toxic substances, electrolyte imbalances, and metabolic disturbances can contribute to nerve damage and dysfunction. Therefore, lumbosacral plexopathy should be included in the differential diagnosis of such cases, presenting with sudden leg weakness.

Source: Frontiers in Musculoskeletal Disorders

DOI: 10.3389/fmscd.2025.1528162

Authors: E. G. Seliverstova, M. V. Sinkin, A. A. Grin

Institutions: Research Institute of Emergency Care, N.V. Sklifosovsky Research Institute of Emergency Medicine, Pirogov Russian National Research Medical University

Language: English

Topic: Muscle and Compartmental Disorders

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,353