Systematic Review: Effectiveness of Probiotic Giving as Additional Therapy in Atopic Dermatitis Patient
Year: 2024
Type: review
Study design: Systematic Review
Abstract: Background: Atopic dermatitis (AD), also known as eczema, is a chronic inflammatory skin condition affecting the epidermis and dermis. It is triggered by a combination of environmental and genetic factors, leading to symptoms such as polymorphic rashes and intense itching. Objective: This systematic review aims to evaluate the effectiveness of oral probiotic supplementation as an adjunct therapy for individuals with atopic dermatitis. Methods: The literature was reviewed by searching two electronic databases, Google Scholar and PubMed, resulting in the inclusion of eight studies that collectively involved 347 AD patients. Results: The findings indicate that probiotic supplementation can significantly reduce the severity and incidence of atopic dermatitis. This effect is attributed to the inhibition of Th2 cell activity and a reduction in pro-inflammatory cytokines, including TNF-α and IgE, which are known contributors to the pathophysiology of AD. Conclusion: Probiotics present a promising alternative for the prevention and management of atopic dermatitis, potentially enhancing patient outcomes.
Authors: Evangelista Maria Pangkahila, Made Yudha Asrithari Dewi, Agustinus I Wayan Harimawan
Institutions: Warmadewa University, Udayana University
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4407569940