Year: 2025
Type: article
Abstract: An extensive examination of the prior developments of drug delivery systems (DDS) based on nanoparticles will be covered in this study, along with novel research findings on the therapeutic improvement of antiretroviral therapy. Practitioners will be able to provide medications to target particular body parts thanks to the use of nanoparticle DDS. The application of nanoparticles as a DDS is having a discernible therapeutic impact in the treatment of cancers. DDS will also be used in medical imaging to illuminate brain function, cancers, or other body cellular activities. There is great promise for using nanoparticle DDS to enhance human health. Its unique features, such as its nanoscale structure, improved permeability and retention capacity, higher surface-area-to-volume ratio, ability to be functionalized on the surface etc., make it a successful drug delivery method for the administration of antiviral treatments. The more important variables that impact target-specific drug delivery, optimal cellular uptake, degree of opsonization by host immune cells, drug retention time, transcytosis, biological half-life extension, in vivo stability, and cytotoxicity are nevertheless the size, shape, charge, and surface topology of the nanoparticles. The review will shed light on the significant obstacle of clinical safety and efficacy as well as the elaborate role of drug delivery based on nanotechnology. Keywords: Nanotechnology, Dendrimers, Controlled drug release, Nanoparticle, Nanospheres.
Authors: Sanket P. Shinde, Christopher Benjamin Lobo, Harshal Suresh Singh Rajput, Gaurav Fulchand Nikam
Institution: Dr. Babasaheb Ambedkar Technological University
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4407572653