Detections of rare enterovirus C105 linked to an emerging novel clade, Spain, 2019 to 2024
Year: 2025
Type: article
Study design: Case Report
Abstract: Enterovirus (EV)-C105 is a rare genotype not previously detected in Spain. Between 2019 and 2024, we detected EV-C105 in respiratory samples of five patients, through routine EV surveillance. Three cases had respiratory illness and two were hospitalised for neurological illness. Four of the five sequenced strains belonged to an emerging clade (C1), defined by four novel nonsynonymous mutations in key antigenic epitopes. We recommend reinforced clinical awareness and EV genomic surveillance, including respiratory samples, even when symptoms are neurological.
Source: Eurosurveillance
Institutions: Instituto de Salud Carlos III, Centro Nacional de Microbiologia, Centro de Investigación Biomédica en Red, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Centro de Investigación Biomédica en Red Enfermedades Infecciosas, Hospital de Sant Pau, Hospital General Universitario Morales Meseguer, Hospital General Universitario de Elche
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4407584920