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Spotlight on the Unusual: A Case Report of Adrenal Angiosarcoma Presenting as an Abdominal Mass

Year: 2025

Type: article

Abstract: This case discusses the challenges of diagnosing adrenal angiosarcoma, a rare and aggressive malignancy that constitutes an exceptionally small proportion of adrenal tumors. Angiosarcomas originate from blood or lymphatic vessel endothelium, with soft tissue and cutaneous forms being more prevalent than those arising in visceral organs such as the adrenal glands. This report describes a 47-year-old female patient who presented with a large right adrenal mass identified through imaging and was subsequently diagnosed with primary adrenal angiosarcoma. This disease may remain asymptomatic or present with nonspecific symptoms, making early detection challenging. Prompt identification and surgical management are essential, as the tumor exhibits a high propensity for aggressive behavior and metastatic spread. While no standardized treatment guidelines exist, adrenalectomy and systemic therapy are commonly employed strategies. Prognosis remains unfavorable, often influenced by tumor size, necrosis, and metastatic involvement at diagnosis. This case highlights the importance of accurate diagnostic methods and early intervention to enhance patient outcomes.

Source: Cureus

DOI: 10.7759/cureus.78968

Authors: Ermilo Echeverría-Ortegón, Javier Casillas, Luis Pech, Isabella Canto

Institutions: Universidad Marista de Mérida, University of Miami, Jackson Memorial Hospital

Language: English

Topic: Vascular Tumors and Angiosarcomas

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4407589981