Work

Comparative Phase Solubility Analysis of Olanzapine by 24 Optimization Techniques with Different Water-Soluble Carriers

Year: 2025

Type: article

Abstract: Background The solubility of medications significantly affects their absorption and therapeutic effectiveness. Drugs with poor solubility often faces challenges in formulation development leading to low bioavailability and fluctuations in blood concentration. Olanzapine, an atypical antipsychotic drug used in treating schizophrenia, exemplifies this issue with its low water solubility and subsequent low bioavailability. Materials and Methods This study explores the enhancement of olanzapine

Source: International Journal of Pharmaceutical Investigation

DOI: 10.5530/ijpi.20250074

Authors: Revathi Sundaramoorthi, Anitha Pavadai, Jenifer Sathappan, Senthil Rajan Sivakumar

Institution: Sri Balaji Vidyapeeth University

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4407616484