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Serological Methods in the Diagnosis of Lyme Disease: A Challenge in Laboratory Practice

Year: 2024
Type: article
Abstract: Lyme disease is caused by bacteria of the Borrelia burgdorferi sensu lato complex and is the most common tick-borne infection in Europe and North America. Serological methods are approved for laboratory diagnosis, and the CDC continues to recommend a two-step algorithm for their use. However, serological methods have significant limitations that must be considered when interpreting results. We reviewed literature sources with a focus on the standard two-tiered testing (STTT), which is applied in our country, and the modified two-tiered testing (MTTT).
Language: English
Subfield: Parasitology
Open Access status: diamond
OpenAlex ID: W4407665403
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Related to: 10