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Advanced Technology Clinic Provides Personalized Approach to Pediatric Epilepsy Surgery: Early Data and Future Directions.

Year: 2025

Type: article

Abstract: Objective: Postoperative improvement in seizures may impact quality of life. We examined the relationship between reduced seizure burden and quality of life in a surgical epilepsy clinic. Methods: We reviewed data from all children who received epilepsy surgery at our center. Surgeries were classified as palliative or definitive based on the seizure outcome goals. We collected demographics, surgical data, Engel classification, and quality of life outcomes. Results: Between 2016 and 2024, 282 patients underwent 338 surgeries. In the definitive surgery group, 66 patients (58%) attained an Engel 1 outcome at six months and 46 patients (58%) at 24 months. In the palliative surgery group, six patients (7%) attained an Engel 1 outcome at six months. At 12 months, 75% of patients who attained Engel 1 reported lower depression scores. Conclusion: Improvement in seizure burden and quality of life outcomes following epilepsy surgery may be related. Further outcomes research is required.

Source: PubMed

Authors: Esra Pehlivan, John Zempel, Janette Coble, Sara Graves, Sean McEvoy, Matt Smyth, Kwee Liu Lin Thio, Christina Gurnett, Jarod Roland, Réjean M Guerriero, Stuart R Tomko

Institutions: Washington University in St. Louis, Johns Hopkins University, Johns Hopkins All Children's Hospital

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4407675910

FWCI:

Cites: 32

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Related to: 10