Work

Prevalence and Doppler Indices of Late‐Onset Fetal Growth Restriction at a Single University Hospital in Southern Thailand

Year: 2025

Type: article

Abstract: OBJECTIVES: To evaluate the prevalence of late-onset fetal growth restriction (FGR), and comprehensively assess maternal and fetal Doppler indices by comparing the Doppler measurements of the uterine artery (UtA), umbilical artery (UA), umbilical vein (UV), middle cerebral artery (MCA), and ductus venosus (DV) between normal and FGR groups. METHODS: This prospective study enrolled 306 singleton pregnant women at ≥ 32 weeks' gestation between June 1, 2023 and April 30, 2024. Fetal biometry and Doppler indices were measured via transabdominal ultrasonography by a single operator. The Mann-Whitney U test was used for statistical comparison. RESULTS: Late-onset FGR prevalence was 4.9% (15/306). The FGR group had a significantly higher UtA pulsatility index (PI) and lower cerebroplacental ratio (CPR), cerebral-placental-uterine ratio (CPUR), and UV blood flow normalized for fetal abdominal circumference (UVBF/AC) compared to the normal group. CONCLUSION: Late-onset FGR prevalence was approximately 5%. The higher UtA-PI and lower CPR, CPUR, and UVBF/AC in the FGR group indicated mild placental insufficiency.

Source: Journal of Clinical Ultrasound

DOI: 10.1002/jcu.23948

Authors: Wattanan Watthanasathitnukun, Chitkasaem Suwanrath, Natthicha Chainarong, Chusana Petpichetchian, Chutinun Leelarujijareon

Institution: Prince of Songkla University

Language: English

Topic: Pregnancy and preeclampsia studies

Subfield: Obstetrics and Gynecology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Prince of Songkla University, Faculty of Medicine, Prince of Songkla University