Work

Visible‐Light‐Induced Catalyzed C─H/N─H Cross Coupling of Quinoxalin‐2(1 H )‐ones with Aliphatic Amines Using Mesoporous Graphitic Carbon Nitride

Year: 2025

Type: article

Abstract: In this study, we report a visible‐light‐induced catalyzed C─H/N─H cross coupling of quinoxalin‐2(1 H )‐ones with aliphatic amines using DABCO (1,4‐diazabicyclo[2.2.2]octane) assisted mpg‐C 3 N 4 (mesoporous graphitic carbon nitride). This reaction yields 3‐aminoquinoxalin‐2(1 H )‐ones in moderate to high yields under room temperature conditions in tetrahydrofuran as solvent and O 2 as the sole oxidant. This method displays a good functional group tolerance, requires mild reaction conditions, and enables easy recovery and reuse of the photocatalyst (4 recycles). This pathway to amination, which is predicated upon the use of DABCO as both a base and an electron transfer agent, reveals through a preliminary mechanistic investigation that the reaction involves a radical process.

Source: ChemistrySelect

DOI: 10.1002/slct.202405537

Authors: Xueying Lin, Congxuan Fan, Mushou Cai, Guangliang Song, Hongjun Zhu

Institution: Nanjing Tech University

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: Key Technologies Research and Development Program, National Key Research and Development Program of China

Awards: G2008821386, G380924285