Work

Application of Spatial Omics in the Cardiovascular System

Year: 2025

Type: article

Abstract: Cardiovascular diseases constitute a marked threat to global health, and the emergence of spatial omics technologies has revolutionized cardiovascular research. This review explores the application of spatial omics, including spatial transcriptomics, spatial proteomics, spatial metabolomics, spatial genomics, and spatial epigenomics, providing more insight into the molecular and cellular foundations of cardiovascular disease and highlighting the critical contributions of spatial omics to cardiovascular science, and discusses future prospects, including technological advancements, integration of multi-omics, and clinical applications. These developments should contribute to the understanding of cardiovascular diseases and guide the progress of precision medicine, targeted therapies, and personalized treatments.

Source: Research

DOI: 10.34133/research.0628

Authors: Yuhong Hu, Hao Jia, Hao Cui, Jiangping Song

Institutions: Chinese Academy of Medical Sciences & Peking Union Medical College, Fu Wai Hospital, State Key Laboratory of Cardiovascular Disease, Kunming Medical University, Fuwai Yunnan Cardiovascular Hospital

Language: English

Topic: Single-cell and spatial transcriptomics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,500