Comparison of Crystallized Phenol Application and the Karydakis Flap Technique in the Treatment of Sacrococcygeal Localized Pilonidal Sinus Disease
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: BACKGROUND: Pilonidal Sinus Disease (PSD) is a chronic condition characterized by inflammation in the sacrococcygeal region, most commonly affecting young adults. The prevalence of PSD is estimated at about 6 cases per 100,000 individuals, with a higher incidence observed in males, who are 3 to 4 times more likely to develop the condition compared to females. This study aimed to compare the rates of wound complications between two treatments: Crystallized Phenol Application and the Karydakis Flap Technique, in the management of sacrococcygeal PSD. METHODS: This Randomized Controlled Trail study included a total of 80 patients, randomly divided into two groups. Group A received Crystallized Phenol Application, while Group B underwent the Karydakis Flap Technique. Demographic information such as age, gender, weight, height, BMI, and duration of the disease were collected. Post-operative wound complications, including dehiscence and infection, were monitored. Statistical analysis was conducted using t-tests for continuous data and Chi-square tests for categorical variables to identify any significant differences between the two groups. RESULTS: The analysis revealed no significant differences between the two groups regarding age (p = 0.63), gender (p = 0.42), weight (p = 0.40), height (p = 0.36), BMI (p = 0.22), or duration of the disease (p = 0.50). Wound complications were observed in 5 patients from Group A and 3 patients from Group B, with no statistically significant difference between the groups (p = 0.56). CONCLUSION: Both the Crystallized Phenol Application and the Karydakis Flap Technique yielded comparable results in terms of wound complications and other patient-related factors. Larger studies are recommended to confirm these findings.
DOI: 10.62019/dfwwbh43
Authors: Dr. Shehzad Farooq, Dr. Muhammad Lateef, Dr. Muhammad Sohaib, Dr. Muhammad Hasnain Hameed, Dr. Tuqeer Arshad, Dr. Jabbar Hussain Bali
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4407711510