Neuroendocrine Prostate Tumor: A Case Report and Literature Review
Year: 2025
Type: article
Study design: Case Report
Abstract: Neuroendocrine Prostate Tumor: A Case Report and Literature Review - Neuroendocrine prostate cancer is a rare entity with a poor prognosis. It can present in a pure form (small or large cell neuroendocrine carcinoma) or mixed, that is to say associated with an adenocarcinomatous contingent. Rarely diagnosed de novo, primary large cell tumors are exceptional. The development of molecular analysis tools has provided important elements for understanding the origin of this histological subtype and the signaling pathways involved. This could also help to identify diagnostic and prognostic biomarkers as well as potential molecular targets. We report here the case of a 63-year-old patient diagnosed with mixed prostate cancer with large cell neuroendocrine component at a localized stage and detail the particularities of his management. Keywords: Prostate Cancer, Neuroendocrine Tumor, Adenocarcinoma, PSA, Hormone Therapy, Surgery.
Authors: Chouef Jihane, Medyouni Hajar, Ouafki Imane, Siyouri Oumaima, Elhakym Samia, Mhirech Samia, Amaadour Lamiae, Oualla Karima, Benbrahim Zineb, Arifi Samia, Mellas Nawfel
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4407720157