Work

[Type II Leydig cell hypoplasia caused by LHCGR gene mutation: a case report].

Year: 2025

Type: article

Abstract: gene. The patient was ultimately diagnosed with type II Leydig cell hypoplasia. Type II Leydig cell hypoplasia presents a broad spectrum of clinical phenotypes, characterized by a lack of parallel function between Leydig cells and Sertoli cells, and significant individual variability in spermatogenesis and gender assignment. This condition should be considered when there is poor Leydig cell function but good development of Wolffian duct derivatives.

Source: PubMed

DOI: 10.7499/j.issn.1008-8830.2410074

Authors: Ke-Xin Jin, Zhe Su, Yan-Hua Jiao, Li-Li Pan, Xian-Ping Jiang, Jian-Chun Yin, Jia-Qiang Li

Institution: Shenzhen Children's Hospital

Language: English

Topic: Sexual Differentiation and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4407720295

FWCI:

Cites: 14

Cited by:

Related to: 10