Surgical outcome of cerebellopontine angle meningiomas via a retrosigmoid approach: A single-center experience in Vietnam
Year: 2025
Type: article
Study design: Observational Study
Abstract: Objectives: Evaluate the surgical results of cerebellopontine angle (CPA) meningiomas via a retrosigmoid approach. Methods: This study investigated the outcomes of the retrosigmoid approach for CPA meningiomas in 36 patients. Demographic characteristics and surgical outcomes were recorded on admission, post-operation for 3-month, and 12-month follow-up. Surgical outcome was measured by using the Glasgow Outcome Scale (GOS), the extent of resection (EOR), and cranial nerve functions. Statistical analysis was conducted to identify the factors influencing outcomes. Results: The data showed 69.4 % of the patients had a tumor with a size over 30 mm. Intraoperatively, the most common site of dural attachment was supra-meatal (33.3 %) and only one patient had a tumor centered on internal acoustic meatus (IAM). Gross total resection was achieved in 25 patients (69.4 %). Good functional status (GOS 4-5) at discharge was 77.8 % and at 12-month follow-up was 88.9 %. Large tumors (>30 mm) with brainstem compression, brainstem edema, flow-void within tumor, and invasion of cranial foramina (Meckel's cave, jugular foramen) significantly impacted the outcome (p < 0.05). Tumors invading the IAM were associated with a significantly higher risk of facial palsy compared to those without IAM involvement. Besides, aspiration pneumonia was strongly related to poor outcomes (p < 0.05). Conclusion: Most CPA meningiomas can safely be resected via a retrosigmoid approach, highlighting the importance of meticulous surgical technique and post-operative care. However, careful consideration of factors like tumor size, flow-void within tumor, brainstem compression, brainstem edema, and potential complications (due to invasion of cranial foramina) can help optimize surgical strategy and improve long-term functional outcomes.
Source: Heliyon
Authors: Hong-Hai Do, Luan Trung Nguyen Dao, Minh-Anh Nguyen, Thanh-Lam Nguyen
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,270
OpenAlex ID: W4407727718