Work

Evaluation of the Therapeutic Efficacy of Moist Wound Healing After Fractional CO 2 Laser Surgery

Year: 2025

Type: article

Abstract: ABSTRACT Background With the popularization of laser therapy, an increasing number of patients are undergoing fractional CO 2 laser therapy. It is particularly important to exercise caution and accelerate wound healing after laser surgery. Aims This study aimed to examine the clinical efficacy of moist wound healing after fractional CO 2 laser therapy. Patients/Methods A total of 15 individuals volunteered to undergo fractional CO 2 laser therapy. The facial skin was irradiated with a fractional CO 2 laser in the deep mode, with an energy of 15 mJ/cm 2 and a density of 5%. The left and right sides of the faces were considered the observation and control groups, respectively. After laser therapy, medical cold compress patches were applied on the skin in the control group once a day for approximately 10–15 min, whereas erythromycin ophthalmic ointment was applied on the skin in the observation group 6 times daily for wound care. The wound healing time, duration of erythema, and occurrence of adverse reactions were monitored in both groups. Results The observation and control groups received different nursing interventions. The time to regression of erythema and swelling was significantly shorter in the observation group than in the control group. In addition, the scab formed at the wound site was thinner, and shedding was faster in the observation group than in the control group. The Clinical Erythema Assessment score of the observation group was significantly lower than that of the control group ( p < 0.05). The wound healing time was 5.73 ± 0.70 days in the observation group and 7.73 ± 0.72 days in the control group, with the difference being statistically significant ( p < 0.05). After 30 min and 12 h of nursing intervention, the Visual Analog Scale score of the observation group was significantly lower than that of the control group ( p < 0.05). However, after 24 h of treatment, neither group showed significant pain. Both groups showed varying degrees of acne, pustules, and exudation, which subsided within 7 days. Furthermore, the control group had 2 cases of mild pigmentation, which resolved within 3 months. Neither group experienced adverse reactions such as skin infection, depigmentation, or scar formation. Conclusion Moist healing therapy can accelerate wound healing and reduce the duration of erythema and edema after fractional CO 2 laser therapy, demonstrating potential clinical application value.

Source: Journal of Cosmetic Dermatology

DOI: 10.1111/jocd.70079