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Anterior Versus Posterior Lumbar Interbody Fusion at L5-S1 in Hybrid Surgery for Adult Spinal Deformity: A Propensity Score Matching Analysis of Radiographic Results, Mechanical Complications, and Clinical Outcomes

Year: 2025

Type: article

Abstract: Objectives: The aim of this study was to compare the radiographic results, mechanical complications, and clinical outcomes between anterior and posterior lumbar interbody fusion at L5–S1 (ALIF51 and PLIF51 groups, respectively) using a matched cohort of patients undergoing long fusion for adult spinal deformity (ASD). Methods: Patients who underwent hybrid surgery of ≥5-level fusion to the pelvis with a minimum follow-up duration of 2 years were included. The baseline characteristics of the groups were controlled using a propensity score matching analysis. The radiographic results, mechanical complications such as proximal junctional kyphosis/failure and metal failure, and clinical outcomes were compared between the groups. Results: In total, 79 patients were assigned to each group with comparable baseline data, except for a higher frequency of anterior column realignment procedures in the PLIF51 group than in the ALIF51 group (49.4% vs. 31.6%). At the last follow-up, L5–S1 segmental lordosis (SL) was significantly greater in the ALIF51 group than in the PLIF51 group (12.1° vs. 7.3°, p < 0.001). The final C7–sagittal vertical axis (SVA) was significantly smaller in the ALIF51 group than in the PLIF51 group (25.4 mm vs. 35.5 mm, p = 0.032). However, other global sagittal parameters were comparable between the groups. The mechanical complication rates, including metal failure at L5–S1, and the final clinical outcomes were comparable between the groups. Conclusions: ALIF51 has modest advantages over PLIF51 in terms of better restoring L5–S1 SL and C7–SVA with avoiding more invasive procedures above the L5–S1 levels. Other sagittal parameters, mechanical complication rates, and clinical outcomes did not differ between the groups.

Source: Journal of Clinical Medicine

DOI: 10.3390/jcm14051431

Authors: Se-Jun Park, Dong-Ho Kang, Jin-Sung Park, Minwook Kang, Chong-Suh Lee, Kyunghun Jung

Institutions: Samsung Medical Center, Bumin Hospital Group

Language: English

Topic: Scoliosis diagnosis and treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137