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The role of the complex approach in the diagnostic evaluation and treatment of a patient with hypertrophic obstructive cardiomyopathy with a midventricular gradient

Year: 2024
Type: article
Study design: Case Report
Abstract: We present a clinical case of a patient with hypertrophic cardiomyopathy (HCM) characterized by an inverted septal curvature phenotype, accompanied by angina and presyncope symptoms. Patients with this type of presentation remain a diagnostic and therapeutic challenge due to their association with midventricular obstruction, apical aneurysm formation, and an increased risk of arrhythmias and sudden cardiac death (SCD). Their treatment and follow-up require a multidisciplinary approach to improve quality of life and prognosis. Various imaging modalities were applied in this case, confirming the presence of severe left ventricular hypertrophy, posterior wall hypertrophy of the right ventricle, and a midventricular gradient. Magnetic resonance imaging (MRI) demonstrated fibrosis involving approximately 25% of the myocardium. The patient was stratified as high-risk patient for SCD. To improve the patient’s quality of life and prognosis, pharmacological therapy was optimized, and an implantable cardioverter-defibrillator (ICD) was placed.
Authors: H. Varnaliyska, R. Stoycheva, A. Popova, D. Dimitrov, A. Osmanov, V. Groudeva, D. Trendafilova
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4407775744
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Related to: 10