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NAE1-mediated neddylation coordinates ubiquitination regulation of meiotic recombination during spermatogenesis

Year: 2025

Type: article

Abstract: NAE1-mediated neddylation regulates ubiquitination during meiosis and is involved in the stabilization of recombination proteins related to crossover differentiation. We provide cytological evidence for the neddylation-ubiquitination system (NUS) in mammalian meiotic recombination during spermatogenesis.

Source: Theranostics

DOI: 10.7150/thno.107843

Authors: Yu Xi, Chenjia Gong, Zhe Zhang, Feiyin Zhu, Ying Zhang, Yanlin Tang, Liying Yan, Hui Jiang, Jie Qiao, Qiang Liu

Institutions: Peking University Third Hospital, Peking University, Center for Life Sciences, Peking University First Hospital

Language: English

Topic: Ubiquitin and proteasome pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,671

OpenAlex ID: W4407776413

FWCI: 1.004

Cites: 2

Cited by: 4

Related to: 10