Epidemiology and Clinical Features of Mpox in Jakarta, Indonesia, August 2022–December 2023

Year: 2025

Type: article

Abstract: BACKGROUND/OBJECTIVE: This study explores the epidemiology and clinical features of re-emerging mpox in Jakarta, Indonesia. METHODS: This study used a retrospective study design to describe the epidemiological data, clinical features, and mortality of mpox patients from August 2022 to December 2023. In addition, this study also aims to identify the differences in both the epidemiology and clinical features of mpox in people living with HIV (PLHIV) and in non-HIV patients (non-PLHIV). RESULTS: Our study shows that, as of the end of December 2023, 59 mpox cases were treated in Jakarta. All of the mpox cases in Jakarta were diagnosed in males, mainly found in MSM (91.5%), and PLHIV (78%). Most patients would manifest with fever, rash, and skin lesions. Syphilis was found as a concomitant infection in this group (22/59, 37.2%). Severe manifestations were found among PLHIV without antiretroviral therapy (ART). CONCLUSIONS: Mpox cases in Jakarta were all found in males and most of them were PLHIV. There are various manifestations of mpox; however, since immunosuppressed patients could present differently, a strong surveillance and vaccine notification system, cautious management, and spreading vaccination awareness are needed to prevent and treat mpox.

Source: Vaccines

DOI: 10.3390/vaccines13030210

Institutions: University of Indonesia, Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo, Universitas Trisakti

Language: English

Topic: Poxvirus research and outbreaks

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,258

Funders: Universitas Indonesia, Fakultas Kedokteran, Universitas Indonesia

OpenAlex ID: W4407785757