From Fragmented Data to Integrated Drug Development in Asphyxiated Neonates Undergoing Therapeutic Hypothermia
Year: 2025
Type: article
Abstract: sponsorship: This research was funded by a Senior Research Grant from the Research Scientific Foundation-Flanders (FWO)-G0D0520N, I-PREDICT: Innovative Physiology-based pharmacokinetic model to pREdict Drug exposure In neonates undergoing Cooling Therapy, and by a KU CELSA research project (Central Europe Leuven Strategic Alliance, CELSA/24/022). The research activities of A. Smits are supported by a Senior Clinical Investigatorship of the Research Foundation-Flanders (FWO) (18E2H24N). (Senior Clinical Investigatorship of the Research Foundation-Flanders (FWO))
DOI: 10.1002/jcph.70012
Authors: Karel Allegaert, Pieter Annaert, Anne Smits
Institutions: Erasmus MC, KU Leuven, Universitair Ziekenhuis Leuven
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,150
Funders: Fonds Wetenschappelijk Onderzoek, Vlaamse regering, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Child Health and Human Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G2062956980, G2358149559, G2593500855, G2603685397, G3112965049, G3122344010, G4306857565, Repurposing Paracetamol to ImpRove NEOnatal asphyxia (REPAIR-NEO study), G5139652136, Physiologically-Based Pharmacokinetic Modeling to Guide Drug Dosing in Children with Obesity, G55644326, Application of Physiologically-Based Pharmacokinetic Modeling to Characterize Drug-Drug Interactions in Infants, Personalized pharmacotherapy in neonates: from (patho)physiology to innovative pharmacokinetic and pharmacodynamic tools, UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program, I-PREDICT: Innovative Physiology-based pharmacokinetic model to pREdict Drug exposure In neonates undergoing Cooling Therapy
OpenAlex ID: W4407792123