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Ohauamines A–D, Structurally Unprecedented Tricyclic Depsi-tripeptides from the New Zealand Ascidian Pycnoclavella kottae

Year: 2025

Type: article

Abstract: Four structurally unprecedented tricyclic depsi-tripeptides, ohauamines A–D ( 1 – 4 ), were isolated from the New Zealand endemic ascidian Pycnoclavella kottae . Planar structures were elucidated by extensive use of 1 H-, 13 C-, and 15 N-based NMR experiments, with absolute configurations established by computational methods.

Source: Journal of Natural Products

DOI: 10.1021/acs.jnatprod.5c00033

Authors: Dan Chen, Florent Rouvier, Robert Keyzers, Marie-Lise Bourguet-Kondracki, Jean Michel Brunel, Melissa M. Cadelis, Brent R. Copp

Institutions: University of Auckland, Inserm, Aix-Marseille Université, Membranes et Cibles Thérapeutiques, Victoria University of Wellington, Centre National de la Recherche Scientifique, Muséum national d'Histoire naturelle, Molécules de Communication et Adaptation des Micro-organismes

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: Royal Society Te Apārangi, Ministry of Business, Innovation and Employment

Award: G3158650822

OpenAlex ID: W4407792606

FWCI: 0.97

Cites: 10

Cited by: 2

Related to: 10