[A case of decompensated hepatitis B virus-related cirrhosis combined with renal injury rescue treatment using tenofovir amibufenamide tablet].
Year: 2024
Type: article
Study design: Case Report
Abstract: 慢性乙型肝炎和乙型肝炎肝硬化人群，推荐长期服用核苷（酸）类似物（NAs）抗病毒治疗，药物的安全性备受关注。艾米替诺福韦（TMF）作为治疗慢性乙型肝炎的NAs一线抗病毒药物，肝细胞靶向性较高，肾脏安全性较好，近几年被应用于临床挽救治疗。现报道TMF挽救治疗1例乙型肝炎肝硬化失代偿期、肝癌介入术后、长期服用富马酸替诺福韦二吡呋酯的患者资料，近期出现大量蛋白尿、肾功能不全，肾穿刺病理学检查显示为膜增生样肾小球肾炎；调整为TMF后，患者肾功能恢复，尿蛋白减少，临床症状好转，取得较好疗效，为此类患者选择何种NAs提供了一定的参考价值。.
Source: PubMed
Institutions: Shanxi Medical University, Shanxi Academy of Medical Sciences
Language: English
Topic: Hepatitis B Virus Studies
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4407800708