Year: 2025
Type: article
Abstract: Myocardial infarction is a severe clinical manifestation of acute coronary syndrome.Despite advancements in early treatment, the long-term impact of ischemia-related heart damage remains a major cause of heart failure.The immune response plays a role in cardiac complications following myocardial infarction.T lymphocytes exhibit different phenotypes after myocardial infarction.CD4⁺ T cells differentiate into multiple subsets, contributing to immune regulation, promoting angiogenesis, regulating scar formation, and influencing cardiac remodeling.CD8⁺ T cells are primarily cytotoxic and may directly kill cardiomyocytes, promoting adverse ventricular remodeling in myocardial infarction.Understanding the role of T cells at each stage of myocardial infarction could identify potential targets for developing new treatments
Source: Research Review
Authors: Shufeng Zhong, Hao Li, Junqiang Liu
Institution: South China University of Technology
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4407816977