Factors associated with scoliosis development in patients with congenital diaphragmatic hernia: A single-center retrospective study
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Scoliosis is the most frequent complication of musculoskeletal abnormalities in patients with congenital diaphragmatic hernia, but the factors that related to its development and severity remain largely unknown. This study aimed to investigate the clinical factors associated with the development and severity of scoliosis in patients with congenital diaphragmatic hernia. METHODS: Thirty-two patients admitted to the neonatal intensive care unit for congenital diaphragmatic hernia at the University of the Ryukyus Hospital between 2004 and 2019 were retrospectively analyzed, particularly those who were discharged alive and had available chest radiographs at 4-5 years of age from medical records. The presence of scoliosis was determined using the chest radiographs. Basic and medical information was also extracted from the patients' medical records. RESULTS: Factors associated with scoliosis development were an Apgar score <7 points, liver prolapse, and intubation period. The Cobb angle exhibited a significant positive correlation with intubation period, hospital stay duration, and tube feeding duration. CONCLUSION: Patients with severe congenital diaphragmatic hernia have a high risk of developing scoliosis and may need to begin comprehensive intervention by a multidisciplinary medical team at an early stage.
Source: Pediatrics & Neonatology
Authors: Sohkun Hoshino, Tomohide Yoshida, Mayumi Tsukayama, Taro Naka, Hiroshi Sekiguchi, Jun Kobayashi, Koichi Nakanishi
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4407819117