Burden of stroke in adolescents and young adults (aged 15–39 years) in South East Asia: a trend analysis from 1990 to 2021 based on the global burden of disease study 2021
Year: 2025
Type: article
Abstract: Background: Stroke is a leading cause of morbidity and mortality globally, yet its burden among adolescents and young adults (aged 15-39 years) in South East Asia (SEA) remains understudied. Understanding regional trends and risk factors in this population is critical for effective prevention and management strategies. This study aims to examine stroke trends from 1990 to 2021, focusing on ischemic stroke, intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) in SEA. Methods: Using data from the Global Burden of Disease (GBD) 2021 study, temporal trends in stroke incidence, mortality, and Disability-Adjusted Life Years (DALYs) were analyzed for the age group 15-39 years. Join point regression analysis was employed to identify significant changes in stroke trends, and gender specific patterns were also assessed. Results: Ischemic stroke cases in SEA increased from 28030.85 to 40836.18, with a slight rise in incidence, particularly affecting males aged 30-39, while female mortality dropped by 23.81%. ICH incidence decreased annually by 0.6692%, with significant reductions in DALYs and mortality, especially among younger age groups and females. SAH incidence declined by 0.2142%, accompanied by a notable reduction in female mortality (31.83%). Countries with lower SDI experienced higher stroke incidence and mortality rates, highlighting socio-economic disparities. Geographic analysis revealed the Philippines had the highest rise in ischemic stroke, while most other countries saw declines in ICH and SAH rates. Conclusion: The study highlights significant progress in managing ICH and SAH, especially among younger populations and females. However, ischemic stroke remains a growing challenge, particularly for males, necessitating targeted interventions to reduce the overall stroke burden.
Source: Frontiers in Stroke
Authors: Prakasini Satapathy, Shubham Chauhan, Shilpa Gaidhane, Ashok Kumar Bishoyi, G. Padma Priya, Karthikeyan Jayabalan, Swati Mishra, Shilpa Sharma, Ganesh Bushi, Muhammed Shabil, Rukshar Syed, Kamal Kundra, Navneet Dev, Sabah Ansar, Sanjit Sah, Quazi Syed Zahiruddin, Shailesh Kumar Samal, Diptismita Jena, Khang Wen Goh
Institutions: INTI International University, Chitkara University, Saveetha University, Datta Meghe Institute of Higher Education and Research, Marwadi University, Jain University, Sathyabama Institute of Science and Technology, Siksha O Anusandhan University, Institute of Medical Sciences and Sum Hospital, Lovely Professional University, University of Cyberjaya, Chandigarh University, Al-Mustaqbal University, Graphic Era University, King Saud University, Korea University, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D.Y. Patil Vidyapeeth, Pune, Karolinska Institutet, Noida Institute of Engineering and Technology Pharmacy Institute, State University of Padang
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,353
OpenAlex ID: W4407828293