Work

Verification of the analytical performance of free triiodothyronine on ALINITY ci ® experience from the biochemistry laboratory of Mohammed VI University Hospital in Oujda

Year: 2025

Type: article

Abstract: The verification of analytical methods is a requirement outlined by the International Organization for Standardization (ISO). This process involves evaluating the performance of an analytical method according to a well-defined protocol and comparing it with pre-established analytical objectives. In our study, we conducted an evaluation of the analytical performance of the free triiodothyronine (FT3) assay using the Abbott kit on the Alinity ci® analyzer in the biochemistry laboratory of Mohammed VI University Hospital in Oujda. The methodology adhered to the recommendations of the French accreditation committee (COFRAC) technical guide SH GTA 04, focusing on the assessment of repeatability and reproducibility. The results demonstrated excellent precision across low, medium, and high FT3 concentrations, with coefficients of variation (CV) within acceptable limits. These findings confirm the reliability of the Alinity ci® system for FT3 measurement, supporting its use in clinical diagnostics. It is important to note that the accuracy and reliability of examination results depend not only on laboratory personnel, equipment, and environmental conditions but also on the methods utilized and their validation or verification.

Source: World Journal of Biology Pharmacy and Health Sciences

DOI: 10.30574/wjbphs.2025.21.2.0147