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Prostatic Adenocarcinoma Presenting as a “Giant” Abdominal Mass on PSMA PET/CT

Year: 2025

Type: article

Abstract: We report a 75-year-old man who presented with an abdominal mass associated with urinary retention. Physical examination revealed an enlarged prostate. Bedside ultrasound demonstrated a very large abdominal-pelvic mass inseparable from the bladder. PSA levels were high at 2393 ng/mL. Transrectal ultrasound-guided biopsy confirmed prostatic acinar adenocarcinoma (Gleason 4+5). PSMA PET/CT scan showed a large, intensely PSMA-avid abdominal-pelvic mass involving the prostate, seminal vesicles, and bladder, with peritoneal metastasis. No osseous metastasis was noted. This case highlights how prostatic adenocarcinoma can present as a giant abdominopelvic mass, clearly illustrated on PSMA PET/CT.

Source: Clinical nuclear medicine open.

DOI: 10.1097/nm9.0000000000000019

Authors: Juncheng Huang, Hoi Yin Loi

Institutions: National University Hospital, National University Health System

Language: English

Topic: Prostate Cancer Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4407834413

FWCI: 0.587

Cites: 8

Cited by: 1

Related to: 10