Contemporary Patterns of End-of-Life Care Among Medicare Beneficiaries With Advanced Cancer
Year: 2025
Type: article
Study design: Observational Study
Abstract: Importance: Considerable efforts have been dedicated to improving the quality of end-of-life care among patients with advanced cancer in the past decade. Whether the quality has shifted in response to these efforts remains unknown. Objective: To examine contemporary patterns of end-of-life care among patients with advanced cancer. Design, Setting, and Participants: This retrospective cohort study used a recent linkage of Surveillance, Epidemiology, and End Results and Medicare data to characterize patterns of end-of-life care. The cohort included fee-for-service Medicare decedents aged 66 years or older who were originally diagnosed with distant-stage breast, prostate, pancreatic, or lung cancers and died between 2014 and 2019. Analyses were conducted between June 1, 2023, and July 31, 2024. Main Outcomes and Measures: Outcomes included monthly use of acute care, systemic therapy, and supportive care (ie, palliative and hospice care and advanced care planning) in the last 6 months of life. Additionally, a claims-based indicator was evaluated of potentially aggressive care in the last 30 days of life, defined as experiencing more than 1 acute care visit, in-hospital mortality, late receipt of systemic therapy, or hospice entry. Results: The study included 33 744 Medicare decedents with advanced cancer (mean [SD] age, 75.7 [6.9] years; 52.1% male). From 6 months before death to month of death, there was an increase in the mean (SE) number of acute care visits (from 14.0 [0.5] to 46.2 [0.5] per 100 person-months), hospice use (from 6.6 [0.4] to 73.5 [0.5] per 100 person-months), palliative care (from 2.6 [0.2] to 26.1 [0.6] per 100 person-months), and advanced care planning (from 1.7 [0.6] to 12.8 [1.1] per 100 person-months). Overall, 45.0% of decedents experienced any indicator of potentially aggressive care. Conclusions and Relevance: This study found persistent patterns of potentially aggressive care, but low uptake of supportive care, among Medicare decedents with advanced cancer. A multifaceted approach targeting patient-, physician-, and system-level factors associated with potentially aggressive care is imperative for improving quality of care at the end of life.
Source: JAMA Health Forum
Authors: Youngmin Kwon, Xin Hu, Kewei Sylvia Shi, Jingxuan Zhao, Changchuan Jiang, Qinjin Fan, Xuesong Han, Zhiyuan Zheng, Joan L. Warren, K. Robin Yabroff
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $5,000
Funders: Pharmaceutical Research and Manufacturers of America Foundation, Pfizer, California Department of Public Health, University of Southern California, National Comprehensive Cancer Network, Centers for Disease Control and Prevention, Agency for Healthcare Research and Quality, University of California, San Francisco, National Cancer Institute
OpenAlex ID: W4407836964
