Work

Synthesis and Preclinical Evaluation of Novel 99mTc-Labeled FR-Targeting Agents with Satisfactory Imaging Contrast and Reduced Renal Uptake

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c02932

Authors: Junhong Feng, Qianna Wang, Guangxing Yin, Yuhao Jiang, Qing Ruan, Peiwen Han, Qingna Xiao, Dajie Ding, Zuojie Li, Jin Du, Junbo Zhang

Institutions: National Medical Products Administration, Beijing Normal University, China Institute of Atomic Energy, China Atomic Energy Authority

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Beijing Municipal Natural Science Foundation, Beijing Nova Program

Awards: G4497121636, 靶向细菌性感染的放射性核素标记抗菌肽衍生物的制备和显像研究, G716361101, 靶向PSMA的99mTc标记含三唑环的谷氨酸-脲衍生物用作肿瘤分子探针的研究, G757220836

OpenAlex ID: W4407837270

FWCI: 2.179

Cites: 39

Cited by: 4

Related to: 10