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Eco-friendly synthesis trend of Sn-V bimetallic nanoparticles and its potential biological applications

Year: 2025

Type: article

Abstract: This investigation outlines the eco-conscious fabrication of tin-vanadium bimetallic nanoparticles (Sn-V BNPs) using Piper longum extract. The crystalline nature of Sn-V BNPs is confirmed by XRD data, with an average crystalline size of 20 nm. Morphological characterization by HRTEM confirms the irregular, polycrystalline structure of the nanoparticles , with an average size of approximately 25–50 nm. The Sn-V BNPs exhibit enhanced anti-inflammatory activity, achieving a maximum inhibition of 91.7 %. They demonstrate potent antidiabetic activity, with an IC 50 of 52 µg/mL in alpha-amylase inhibition. The nanoparticles also show remarkable cytotoxicity activity, with an IC 50 value of 57 µg/mL against MCF-7 lung cancer cells. These findings highlight the promising potential of green-synthesized bimetallic nanoparticles as multifunctional therapeutic agents.

Source: Materials Letters

DOI: 10.1016/j.matlet.2025.138277

Authors: Ramya Raman, Sudhahar Sakkarapani, Bhaskaran Arumugam

Institutions: Presidency College, Alagappa University

Language: English

Topic: Nanoparticles: synthesis and applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,870