Work

Changes in Vertical Jump Parameters After Training Unit in Relation to ACE, ACTN3, PPARA, HIF1A, and AMPD1 Gene Polymorphisms in Volleyball and Basketball Players

Year: 2025

Type: article

Abstract: Background/objectives: The study aims to investigate potential differences in vertical jump performance between elite basketball and volleyball players before and after a standard training session, in comparison to a control group from the general population. The analysis focuses on the influence of selected gene polymorphisms that may contribute to variations in the assessed performance parameters. Aims: The aim was to investigate the influence of ACE (rs4646994), ACTN3 (rs1815739), PPARA rs4253778, HIF1A (rs11549465), and AMPD1 (rs17602729) genes polymorphisms on the combined effects of post-activation potentiation (PAP), post-activation performance enhancement (PAPE), and general adaptation syndrome (GAS), as reflected in vertical jump performance, in elite basketball and volleyball players compared to a control group from the general population. Methods: The effects of PAP at the beginning of the training load (acute exercise), and the combined influences of PAPE and GAS following the training load were evaluated using parameters measured by the OptoJump Next® system (Microgate, Bolzano, Italy). Results: A statistically significant (h, p < 0.05) negative effect of the CT genotype of the AMPD1 gene on jump height was observed in the group of athletes. The CT genotype of the AMPD1 gene negatively impacted on PAPE and GAS adaptive responses (ΔP, Δh, p < 0.001) also in the control group. A positive effect on the power during the active phase of the vertical jump was identified for the II genotype of the ACE gene and the Pro/Ser genotype of the HIF1A gene, both exclusively in the control group (ΔP, p < 0.05). Conclusion: Our findings demonstrate that different gene polymorphisms exert variable influences on the combined effects of PAPE and GAS, as reflected in vertical jump parameters, depending on the participants’ level of training adaptation.

Source: Genes

DOI: 10.3390/genes16030250

Authors: Miroslav Vavak, Iveta Cihova, Katarina Reichwalderova, David Vegh, Ladislava Dolezajova, Miroslava Slaninova

Institution: Comenius University Bratislava

Language: English

Topic: Genetics and Physical Performance

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137