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Synthesis, Characterization, and Anti-Mycobacterial Evaluation of Oxadiazole and Pyrazolone Derivatives

Year: 2025

Type: article

Abstract: Hydrazides and hydrazones are important precursors for synthesizing heterocyclic compounds. This study focuses on the synthesis and characterization of pyrazolone and 1,3,4-oxadiazole derivatives using spectroscopic techniques. These compounds were screened for their anti-mycobacterial activity, showing promising results. Additionally, in silico ADMET predictions were performed to evaluate their chemical properties. The results indicate the potential of these derivatives as effective anti-tuberculosis agents, paving the way for further biological evaluations.

Source: International Journal of Science and Research (IJSR)

DOI: 10.21275/sr25219221505

Authors: Vijay J Desale, Ramesh S Yamgar

Language: English

Topic: Structural and Chemical Analysis of Organic and Inorganic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4407847758

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