Year: 2025
Type: article
Abstract: Innovative drug delivery mechanisms possess the capacity to overcome the constraints of traditional therapeutic methodologies by enhancing bioavailability, targeting accuracy, and minimizing adverse effects. Aquatic biomaterials, obtained from marine life such as algae, fish scales, and marine invertebrates, present distinct benefits for the creation of innovative drug delivery platforms. These biomaterials exhibit biocompatibility, biodegradability, and unique chemical and structural characteristics that render them suitable candidates for encapsulating and releasing therapeutic agents. This investigation examines the potential of aquatic biomaterials in the development of pioneering drug delivery systems, concentrating on their application in nanoparticle-based formulations, hydrogels, and microspheres. The analysis assesses the encapsulation efficiency, release dynamics, and therapeutic effectiveness of aquatic biomaterial-based systems, alongside their capability to target specific tissues or cells. Moreover, the biocompatibility and pharmacokinetic profiles of these systems are evaluated through in vitro and in vivo investigations. The results indicate that aquatic biomaterial-based drug delivery systems can substantially improve the stability, bioavailability, and controlled release of pharmaceuticals, with promising prospects in cancer treatment, antimicrobial interventions, and wound healing. This research emphasizes the potential of aquatic biomaterials to transform medical treatments and lay the groundwork for sustainable, effective, and personalized therapies.
Source: Journal of Neonatal Surgery
Authors: Chiranjeev Singh, Syed Sajid Ali Syed Sabir Ali
Institution: Kalinga University
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4407858182