Work

Study on the use of black phosphorus quantum dots in the treatment of atherosclerosis

Year: 2025

Type: article

Abstract: Atherosclerosis is the pathological basis of cardiovascular disease, and there are no clinical drugs that can safely and efficiently remove atherosclerotic plaques. In this study, black phosphorus quantum dots (BPQDs) were applied to the treatment of atherosclerosis in high fat diet ApoE-/- model mice that BPQDs were given every other day for 3 weeks without changing the high-fat diet. 45.3% atherosclerotic plaque was cleared efficiently within 3 weeks in BPQDs intravenous administration way every other day. The treatment was more effective than traditional statins. The findings suggest that BPQDs have great potential to be applied for clinical prevention and treatment of AS that does not require dietary changes.

Source: Aging

DOI: 10.18632/aging.206205

Authors: Shengwei Zhang, Yiran Ji, Bingxuan Xu, Die Hu, Xue Zhang, Yujian Song, Keke Chen, Yilin Wen, Xiaoxin He, Yun Chen, Tingting Zheng

Institutions: Hong Kong University of Science and Technology, Zhongshan People's Hospital, Peking University Shenzhen Hospital, First People's Hospital of Foshan, Nanjing Drum Tower Hospital

Language: English

Topic: Atherosclerosis and Cardiovascular Diseases

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4407869640

FWCI:

Cites: 44

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Related to: 10