Year: 2024
Type: article
Abstract: Whereas spinal onset ALS is fatal at 3-5 years postdiagnosis, bulbar onset ALS patients has a worse prognosis with an average survival of only 2 years.Paralysis of respiratory muscles and subsequent respiratory dysfunction is the cause of death.In a small minority of patients (3-5%) onset of disease occurs in respiratory muscles [1]. The suspected culprits in the etiology of ALS include glutamate exitotoxicity reactive oxygen species generation, protein misfolding and aggregation, mitochondrialResearch
DOI: 10.36959/459/612
Author: Hernández Bárbara Aymeé
Institution: Cuban Neuroscience Center
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4407943861