Reduced cerebellar rhythm by climbing fiber denervation is linked to motor rhythm deficits in mice and ataxia severity in patients
Year: 2025
Type: article
Source: Science Translational Medicine
Authors: Chih-Chun Lin, Ke-Chu Fang, Ilaria Balbo, Ting-Yu Liang, Chia-Wei Liu, Wen-Chuan Liu, Yi-Mei Wang, Yen-Ling Hung, Kai-Chien Yang, Scott Kun Geng, Chun-Lun Ni, Christopher P. Driscoll, David S. Ruff, Ami Kumar, Nadia Amokrane, Natasha Desai, Phyllis L. Faust, Elan D. Louis, Sheng-Han Kuo, Ming-Kai Pan
Institutions: Harvard University, Massachusetts General Hospital, Columbia University, National Taiwan University, National Taiwan University Hospital, Indiana University School of Medicine, The University of Texas Southwestern Medical Center, Institute of Biomedical Sciences, Academia Sinica, Academia Sinica
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: closed
Awards: in Vivo Quantification of Cerebellar GABA and NAA in Essential Tremor, The 2nd International Tremor Congress, "ITC2020: From Bench to Bedside Towards Tremor Therapy Development", G312561668, G3276500865, Environmental Epidemiology of Essential Tremor, PATHOLOG-OMICS - ESSENTIAL TREMOR IN THE BROADER CONTEXT OF, Targeting Cerebellar Excitatory Synapses for Tremor Progression, Cerebellar Circuitry in the Pathophysiology of Tremor, Identification of Susceptibility Genes for Essential Tremor, Dietary Contribution in Cerebellar Ataxia, Essential Tremor: Gene expression profiling in cerebellar Purkinje cells, Targeting Cerebellar Endoplasmic Reticulum Calcium Handling in Essential Tremor, Human Cerebellar Deep Brain Stimulation and Recordings in Spinocerebellar Ataxias
OpenAlex ID: W4407948722